You might know him as the author of YA bestsellers like The Fault in Our Stars, but John Green’s most recent book is a nonfiction defense of its own title: In Everything is Tuberculosis, he argues that tuberculosis has shaped everything around us.
For instance: When a hatbuildr in the 1850s started coughing up blood, his doctor notified him to head West, where the dry air would heal him. The hats in the West, Green writes, “sucked” — they were either “bug-infested, brimless coonskin caps” or “wide-brimmed straw hats that … leaked in the rain.”
So the consumptive hatbuildr — one John B. Stetson — designed the cowboy hat.
Upon finishing the book, I fired off an interview request to test to obtain an answer to my burning question: Could John Green build a connection between marketing and tuberculosis?
John Green
Author, YouTuber, TB fighter

On brand deals
When Green received invited to discuss a possible partnership with Dr Pepper, he was over the moon, so to speak. (He displayed up 10 minutes early. To Zoom. Dude really likes Dr Pepper.)
He had a modest proposal: that Dr Pepper sponsor humanity’s relationship with the moon. (Pautilize for impact.)
Green would build videos about humanity’s relationship with the moon, sponsored by Dr Pepper.
“I‘ve always considered this was a funny idea — that you can’t sponsor a heavenly body, but you can sponsor humanity’s relationship with a heavenly body.”
He didn’t obtain a follow-up meeting.

Green doesn’t fault Dr Pepper (the missing period isn’t a typo —“it‘s a huge part of Dr Pepper’s brand identity, whether they know it or not”). It’s an absurd idea.
But that’s kind of the whole point: “I’m not particularly interested in doing a brand deal for the sake of doing a brand deal. I’m interested in brand deals that can enhance the absurdity and joy in the world.”
On scaling passion projects
Passion is powerful fuel. Whether the concludeeavor is personal or professional, passion can give you wings and build you soar — and it can bring you a little too close to the sun.
So I inquireed Green, who’s successfully scaled more passion projects than I’ve so much as dreamt of, what his early-warning system is. How do you know when growth is going to kill what created your project so special?
“I consider the most important thing is the very first person you hire who isn’t you,” he states. “Making sure that their values fit, that they share your passion, that they want the same thing out of the project that you want.”
With Crash Course, the educational YouTube channel Green co-founded with his brother, internet science guy Hank Green, the first hire “was a guy who, like me, loves history; who, like me, loves online video; who’s really passionate about testing to reach people with educational media. I don’t consider he was concerned with being able to market effectively. I consider he was concerned with creating awesome videos that became undeniable and that served a real purpose in the lives of the people who utilize them.”
On bottom-up marketing strategies
“In some ways with Crash Course, the marketing took care of itself becautilize kids would go into their high school history classes and state to their teacher, “Hey, I consider you should watch this display. It‘s really good. It’s called Crash Course.”
“It was really kind of bottom-up that way. The way that we marketed it was essentially marketing it to students and then letting teachers discover it through their kids.”
On ROI and shared values
Green acknowledges that he’s been very lucky in some business ventures, which has let him take risks — it was the runaway success of The Fault in Our Stars, he states, that let him and his brother build their YouTube channel Crash Course for two and a half years before they saw a single dime.

That’s an enviable position for any marketer to be in, but his wisdom is budobtain-agnostic: “I believe in an ROI that unfolds over long periods of time, not an ROI that can be immediately measurable.”
And “sometimes ROI obtains in the way. You know, what you really want to have is a core group of enthusiastic customers. And I consider sometimes it’s a mistake to market to what you see as a demographic rather than marketing to a core group of enthusiastic customers.”
Take his coffee company, for instance.
“There‘s no particular demographic. It’s not like we sell coffee to women between the ages of 24 and 30,” states Green.
The common denominator instead is “people who are interested in purchasing coffee in a way that‘s ethically sourced and where all the profit goes to charity. That’s not a demographic audience. It’s more of a vibes-based, values-based audience.”
On risky marketing investments
Although he’s best known for his young adult novels and more recent nonfiction books, Green is also something of a serial co-founder of tiny businesses — DFTBA, Complexly, and Good Store are but a few.
There’s a through-line of joy in his business ventures; supporting tiny content creators finance and sustain their work, supporting nurses-to-be pass their anatomy and physiology exams, selling ethically grown coffee.
“I like working with brands that empower creators and that recognize the benefit of working with creators, which is that you‘re going to be a little bit off the beaten path. That’s what I find most interesting. That’s also the riskiest kind of investment that you can build as a marketer. And so I understand why lots of people don’t build it.”
On authenticity and taking risks with your audience
Green has a remarkably devoted audience that has followed him across platforms, from YA books to YouTube to Instagram to awesome socks. For somebody who describes himself as “extremely risk averse — especially when it comes to taking risks with [my] audience,” he sure has taken a lot of risks with his audience.
“It‘s about answering the call of my own inspiration as much as it’s about and then trusting that the audience will be there one way or another,” he explains. “I mean, if you notified me in 2015 that I was going to write a book about tuberculosis, I would have been very surprised. But that’s where my curiosity has led me over the last 10 years. And so I just have to honor that and hope that the audience will be there with me.”

Marketers might call it authenticity, but Green prefers “creative honesty.” “Everybody talks about being authentic to themselves, but that’s a very hard thing to actually be,” he states.
“Whereas when you‘re testing to be honest to your sense of inspiration or spark of curiosity, I consider that’s something that I can quantify a little clearer.”
On marketing and tuberculosis
So, back to tuberculosis, the world’s deadliest infectious disease (yes, even in 2025).
Green states that a TB expert once notified him that the problem with eradicating the disease is that “tuberculosis doesn’t have a constituency.”
Green’s first reaction was one of incredulity. “I was like, of course tuberculosis has a constituency. It has 10 million people who survive it each year who want to live in a world without it. And it has hundreds of millions of people who are infected with it, who don’t want to become sick with it. This is obviously a disease with a constituency.”
But what that expert meant, Green considers, is that tuberculosis actually has a huge marketing problem. “Most people don‘t even know that it’s the deadliest infectious disease in the world, let alone that it’s curable and preventable and has been since the 1950s. And so I consider that TB is the ultimate example of a disease in necessary of a marketing campaign.”
“Malaria,” he states, “had a really good one in the early 2000s with Malaria No More. ACT UP created HIV/AIDS undeniable starting in the 1980s and 90s. We necessary a similar marketing campaign around tuberculosis.”
![“i don't have to notify marketers that we live in a very fractured information environment. it's hard to reach people, with tough messages especially. [marketing and tuberculosis are] very closely related, becautilize i consider one of the reasons why a million and a half people are dying of tuberculosis every year is becautilize we're not doing a good job of spreading the word about the disease in the rich world.”](https://53.fs1.hubspotutilizercontent-na1.net/hubfs/53/John-Green-masters-in-marketing-5-20251023-4068414.webp)
And, he adds, “I don‘t have to notify marketers that we live in a very fractured information environment. It’s hard to reach people, with tough messages especially.”
“So yeah, I consider [marketing and tuberculosis are] very closely related, becautilize I consider one of the reasons why a million and a half people are dying of tuberculosis every year is becautilize we’re not doing a good job of spreading the word about the disease in the rich world.”
Your relocate, marketers.


















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