Professor Rik Bryan, Professor of Urothelial Cancer Research and Director of the Bladder Cancer Research Centre at the University of Birmingham, declared: “These are very interesting and exciting data and, as with all cancer research, our findings prompt a lot of new questions as well as answers. However, this long-read sequencing approach may allow us to better understand the very earliest alters in the bladder that ultimately lead to the development of a bladder tumour. In turn, that may then allow us to deliver a new type of urine test, but there is still a long way to go.”
Dr Goel declared: “With nothing more than a urine sample and cost-effective sequencing technology, we can uncover the hidden epigenetic signatures of bladder cancer – opening the door to rapider, gentler, and more patient-frifinishly disease detection in the future.”
The data generated by the new approach is extensive, and the team are now starting to develop Artificial Innotifyigence methods that can classify patients based on their DNA methylation patterns, with the ultimate aim to direct them to the optimal treatment pathway.
Source: University of Birmingham
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